Xenograft using Kangaroo Tendon as a Substitute for Ligament Reconstruction
Bone Ligament Tendon (BLT)
University of Sydney
World-first use of kangaroo as a xenograft material in ligament reconstruction and repair
Worldwide there is a growing demand for effective, off-the-shelf reconstructive (ligament graft) material, driven by escalating rates of ligament injuries and younger patient demographics.
Bone Ligament Tendon (BLT), together with Allegra Orthopaedics and University of Sydney are pioneering a novel solution for the orthopaedic reconstruction of ligament injuries and seek to create a manufacturing and global distribution business.
The project aims to manufacture kangaroo-derived ligament xenografts using novel decellularisation and supercritical sterilisation technique that will not impair mechanical performance and will allow a range of surgical reconstruction applications.
The decellularised, sterile kangaroo tendon, which is up to six times stronger than a human anterior cruciate ligament (ACL), will be fixed to the bone using a 3D-printed screw manufactured from bioresorbable Sr-HT-Gahnite. This will ensure that the patient’s body will eventually be free of any synthetic material. This new xenograft and the Sr-HT-Gahnite screws will be supplied to hospitals in a kit, to provide surgeons with an off-the-shelf option for reconstruction surgery.
This collaboration will produce an innovative xenograft material that will redefine the future of ligament reconstruction. The project will give Australian manufacturing and agriculture a global niche, leveraging Australia’s exclusive access to kangaroos.